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Symbol
Name
ID
Hcst
hematopoietic cell signal transducer
MGI:1344360
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal osteoclast differentiation
decreased uterine NK cell number
increased spleen weight
decreased CD8-positive, alpha-beta T cell number
decreased osteoclast cell number
impaired natural killer cell mediated cytotoxicity
abnormal NK T cell physiology
abnormal osteoclast physiology
decreased interferon-gamma secretion
increased interferon-gamma secretion
increased interleukin-4 secretion
increased susceptibility to experimental autoimmune encephalomyelitis
abnormal response to infection
Availability Mouse Genotype
Hcsttm1.1Cln/Hcsttm1.1Cln *
Hcsttm1.1Dnax/Hcsttm1.1Dnax *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory